Career Category
Scientific
Job Description
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat heart disease, obesity and obesity-related conditions, rare diseases, inflammatory conditions and cancer. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Principal Scientist Oligonucleotides
What you will do
Let’s do this. Let’s change the world. In this vital role you will be part of DSTS group within Process Development (PD) which is responsible for the invention, development, and implementation of drug substance manufacturing processes and technologies to advance Amgen's exciting portfolio of synthetic and hybrid assets. Process chemists within our team to apply their training to invent synthetic routes and chemical processes to support drug substance manufacturing from early to late-stage development.
Amgen is currently seeking a talented Principal Scientist who will who will lead the development of efficient and sustainable manufacturing processes, drive capacity expansion projects, and lead technology transfers for oligonucleotides. The candidate will drive technology innovation, provide technical expertise, and develop and mentor staff within the organization. The successful candidate for this role will be experienced in oligonucleotide process development and industrialization with a proven track record of scientific innovation and leadership within the pharmaceutical industry. The role will be located at either our Thousand Oaks, California or Cambridge, Massachusetts campus.
Lead a multidisciplinary project team in the development of sustainable and cost-effective processes for oligonucleotide manufacturing.
Work with cross-functional teams to develop strategies and implementation plans to expand production capacity and improve yield.
Drive oligonucleotide technology innovation
Support cGMP manufacturing and technology transfer to GMP production facilities
Develop strategies to ensure process performance through process understanding, modeling and characterization
Guide successful completion of project deliverables and ensure timelines are met
Work cross-functionally to deliver regulatory documents and support regulatory filings
Serve as a technical expert and keep current in the field of bioconjugate manufacturing
Coach and provide career and scientific / technical advice to colleagues within the organization
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.
Basic Qualifications:
Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable] and 2 years of Scientific experience
OR
Master’s degree and 5 years of Scientific experience
OR
Bachelor’s degree and 7 years of Scientific experience
Preferred Qualifications:
Doctoral degree and 4+ years in the pharmaceutical industry with expertise in oligonucleotide process development
GMP manufacturing and technology transfer to CMOs
Demonstrated functional representation on a CMC or PDT team
Demonstrated ability to work within a dynamic and interdisciplinary environment to achieve results
People-centered leadership skills in building strong teams through mutual trust and respect…