Arzeda is solving some of today's hardest and most meaningful problems, from food and nutrition to sustainable materials and homecare, by designing proteins that have the limitless potential to change everyone's daily life. Our team has developed Intelligent Protein Design Technology™ that merges computational protein design, machine learning, and synthetic biology tools to produce proteins, enzymes, and bio-based processes more efficiently than Mother Nature. A deep tech, mission-driven company, we are passionate about our mission to design novel proteins and products that enhance our lives and protect our planet. At Arzeda, we value a strong desire to learn, innovate, and be continuously challenged.
We are seeking a detail-oriented Senior Associate Scientist to join our highly collaborative Protein Testing team . You'll play a critical role in Arzeda's design-test cycle by generating and characterizing protein that directly informs scientific decisions and supports program advancement . As a rigorous, self-starting experimentalist with hands-on experience in protein expression, purification, and characterization, you'll generate the decision-quality data that drives protein performance improvement. This role is roughly 75% lab work and 25% data analysis, reporting, and collaboration , and reports to a senior member of the team.
This is an onsite role based at Arzeda in Seattle, Washington. Nestled among the historic and artistic neighborhoods of Ballard, Fremont, and Queen Anne, you'll find the right balance of activities and relaxation. Whether you're indulging your inner foodie at one of many unique restaurants, drinking a craft beverage after a day at the beach, or enjoying a picturesque walk through the Sunday Market, you'll be proud to call Seattle your home. Responsibilities
Conduct small and mid-scale expression of bacteria and yeast strains (plate- and flask-based)
Perform small, mid, and large-scale purification of proteins from bacteria and yeast hosts (plate-based, resins, magnetic beads, gravity columns, FPLC)
Perform basic protein quantification and characterization techniques (SDS-PAGE, LabChip, plate-based protein quant methods, etc.)
Collaboratively plan and execute experiments while using your expertise and project awareness to adapt to changes as needed
Grow your coverage of project workflows by executing biochemical assays using the protein you produced
Independently propose, plan, and execute improvement projects to make our workflows more robust, higher throughput, and more reproducible
Contribute to reporting of experimental results and participate in technical discussions during project meetings
Partner with automation, software, and data infrastructure teams to implement robotic liquid handling, assay orchestration, and streamlined data analysis pipelines
Maintain accurate documentation of experimental results within our LIMS system
Support team members with general project activities and other work as assigned
Qualifications
Bachelor’s degree with 4+ years of relevant industry experience OR Master’s degree with 2+ years of relevant industry experience in Biocatalysis, Biochemistry, Chemical Biology, Chemistry or other related field
In-depth knowledge and hands-on experience with protein expression, purification, quantification, and characterization
Experience designing or operating automated experimental workflows and high-throughput systems strongly preferred
Experience evaluating data sets, putting together reports, and presenting findings and/or results from data analysis
Initiative to independently identify, understand, and resolve experimental challenges
Strong attention to detail
Desire to communicate openly within a team and be receptive to feedback and learning opportunities
Adaptable to changing plans as needed to meet goals
Ability to work onsite, Monday - Friday with some occasional weekend work
Ability to lift up to 20 pounds
Nice-to-haves (not required)
Interest in coding or Python for…