AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious disease. But we’re more than one of the world’s leading pharmaceutical companies.
Role Overview
Join us as Associate Director - Patient Safety Risk & Signal Management Product Lead , where you will play a strategic leadership role in shaping and advancing AstraZeneca’s global Patient Safety technology capabilities focused on Signal Management, Signal Detection, Benefit-Risk Evaluation, and Risk Management Planning (RMP).
This role will lead the technology strategy, product delivery, and operational excellence for enterprise safety platforms including NGSMS and ORBIT, alongside broader pharmacovigilance and regulatory ecosystem integrations. You will serve as a key member of the Product IT DevOps organization, partnering closely with Safety Science, Risk Management & Benefit-Risk teams, Regulatory Affairs, Safety Operations, Enterprise Architecture, and external technology partners to deliver scalable, compliant, and data-driven safety solutions supporting global regulatory obligations and proactive patient safety monitoring.
What you'll do
This role requires deep expertise across pharmacovigilance business processes, signal management technologies, risk management planning, product leadership, and regulated technology delivery. The ideal candidate combines strategic product thinking, strong technical competence, and leadership capabilities to drive modernization and innovation across the Patient Safety landscape.
Key Responsibilities:
Product Strategy & Roadmap
Define and implement the strategic product roadmap for Risk & Signal Management platforms, ensuring alignment with evolving global pharmacovigilance regulations, inspection readiness requirements, and AstraZeneca business priorities.
Lead technology strategy and platform evolution for NGSMS and ORBIT
Signal Detection and Signal Validation workflows
Benefit-Risk assessment capabilities
Risk Management Plan (RMP) lifecycle management
Partner with business stakeholders to translate patient safety objectives into scalable digital product capabilities.
Drive product modernization initiatives leveraging automation, AI/ML-enabled analytics, workflow orchestration, and integrated safety intelligence.
Risk & Signal Management Technology Leadership
Serve as the IT Product and Technology SME for Signal Management and Risk Management Capability in Platform model supporting global pharmacovigilance operations.
Provide technical leadership for signal detection and triage workflows and aggregate safety data analysis
Health authority commitments tracking and risk minimization measure management
Periodic safety review processes and signal governance and audit traceability
Contribute and support architecture and integration discussions related to Signal and Risk Management capabilities.
Collaboration & Business Partnership
Collaborate with cross-functional partners across Development value streams and facilitate alignment between business process transformation initiatives.
Act as a trusted advisor to senior leadership on Risk & Signal Management technology strategy and operational improvements.
Process Optimization & Innovation
Identify opportunities to streamline and automate signal management and RMP processes through digital innovation and AI-enabled capabilities.
Drive continuous improvement initiatives across: Signal intake and prioritization; Case trend analysis, Safety data visualization, Risk tracking workflows
Team Leadership & Vendor Management
Lead and mentor a team of IT professionals, consultants, and mentor vendor partners supporting Risk & Signal Management Solutions.
Foster a culture of innovation, accountability, collaboration, and continuous learning.
Monitor delivery milestones, SLAs, deployment schedules, and platform performance metrics.
Essential…