About This Role
As Senior Medical Director, Ophthalmology, you will lead the clinical and strategic development of Biogen’s ophthalmology programs, from early development through regulatory approval and lifecycle management. You will serve as the lead Development representative on cross-functional strategy and development teams, connecting scientific priorities with clinical, regulatory, and business goals.
Reporting to the Head of Immune Mediated and Neurodegenerative Diseases, you will shape program strategy and provide clinical oversight and medical monitoring leadership. Working closely with Research, Medical Affairs, Regulatory Affairs, Corporate Strategy, and other partners, you will guide development decisions and align execution across the portfolio.
What You’ll Do
Lead ophthalmology development strategy as the Development representative on cross-functional teams, aligning research, clinical, and commercial priorities
Develop and execute integrated asset plans, target product profiles, and lifecycle management strategies, incorporating emerging science and clinical insights
Oversee Development deliverables across preclinical, chemistry, manufacturing and controls (CMC), and clinical activities, supporting timelines, scientific rigor, and regulatory readiness
Serve as Ophthalmology Therapeutic Area Lead, guiding clinical trial design and delivery from first-in-human studies through post-marketing
Provide or supervise medical monitoring, including serious adverse event review, medical coding, data interpretation, and safety oversight
Ensure the medical and scientific integrity of study reports, publications, and regulatory documents; author and review clinical sections of INDs, CTAs, NDAs, BLAs, and briefing materials
Partner with Regulatory Affairs on submission strategy, health authority consultations, and advisory committee preparation; represent Biogen with global health authorities
Provide internal and external ophthalmology expertise on disease trends and treatment landscapes, and contribute clinical and scientific assessments of licensing and partnership opportunities
Represent Clinical Development in leadership forums, aligning program priorities, risks, and execution with commercial, regulatory, and technical operations planning
Coach and mentor direct reports and cross-functional colleagues, building scientific excellence, accountability, innovation, and organizational capability
Who You Are
You connect ophthalmology expertise with a strategic view of drug development and translate complex scientific and clinical information into clear decisions. You build alignment across functions, mentor colleagues, and navigate ambiguity while keeping programs moving forward.
Required Skills
Board certified ophthalmologist (MD, DO, or foreign equivalent)
15+ years of experience 8+ years in ophthalmology clinical development
3-5 years of leadership experience within biotech or pharmaceuticals, with direct responsibility for program strategy and execution
Demonstrated success leading ophthalmology clinical programs across multiple development phases
Experience working with global regulatory agencies and presenting at advisory committee meetings
Deep knowledge of ophthalmic diseases, clinical practice, and emerging therapies, with expertise across preclinical, clinical, and regulatory development
Ability to integrate scientific, clinical, and business considerations into development strategy
Ability to communicate complex concepts clearly to executive leaders, regulatory authorities, and external partners
Demonstrated leadership and influence across functions to guide critical development decisions
Ability to navigate ambiguity, anticipate challenges, and develop innovative solutions that advance programs efficiently
Job Level: Management
Additional Information
The base compensation range for this role is: $274,000.00-$376,750.00
Base salary offered is determined through an analytical approach utilizing a combination of…