Job Title
Clinical Research Program Manager (CPM) – Enroll 2.0
Job Location
The position will be based in Princeton, N.J. (currently hybrid) with occasional travel. Requires 2 days per week in our Princeton office. Local candidates only. Resumes without a local location will not be considered.
Job Reports To
Director, Enroll 2.0 Planning & Implementation
Salary Range:
$80,000 – $120,000. Exact compensation will vary based on experience.
Other
Vaccination against COVID-19 is a prerequisite for employment at CHDI Management.
About CHDI Foundation, Inc.
CHDI Foundation, Inc. is a privately funded nonprofit biomedical research organization exclusively dedicated to collaboratively developing therapeutics that will substantially improve the lives of those affected by Huntington’s disease (HD). Our scientists work closely with a network of more than 700 researchers in academic and industrial laboratories around the world in the pursuit of these novel therapies, providing strategic scientific direction to ensure that our common goals remain in focus. This helps bridge the translational gap that often exists between academic and industrial research pursuits and that adds costly delays to therapy development. In its role as a collaborative enabler, CHDI seeks to bring the right partners together to identify and address critical scientific issues and move drug candidates to clinical evaluation as rapidly as possible. Our activities extend from exploratory biology to the identification and validation of therapeutic targets, and from drug discovery and development to clinical studies and trials. More information about CHDI can be found at www.chdifoundation.org
CHDI’s Clinical Team oversees a portfolio of projects that aim to understand the natural progression of HD, develop the best biomarkers and outcome measures for clinical trials, expedite and improve trial execution, and pave relevant regulatory pathways. The team also works with external partners to support their clinical development plans, including academic institutions, government agencies, contract research organizations (CROs), and biotech and pharmaceutical companies.
We are seeking a highly motivated, organized, and detail-oriented self-starter to help manage projects in the clinical portfolio (including but not limited to clinical studies and trials). You will work closely with the team, internal colleagues (scientific, legal, and financial), and external collaborators (CROs, and sometimes academics or biotech and pharmaceutical companies) on all aspects of CHDI’s clinical research and development efforts, with a particular focus on the operational planning, coordination, and delivery of complex, multi-vendor studies.
Job Responsibilities
A Clinical Research Program Manager works closely with study teams, Directors, and others within CHDI in the following areas:
Vendor management Lead end‑to‑end vendor management: selection, onboarding, contract negotiation, renewals, and termination.
Oversee CROs and service providers to ensure alignment with project objectives, quality standards, timelines, and regulatory requirements.
Develop, manage, and monitor project budgets; track invoices, resolve variances, and identify cost‑efficiency opportunities.
Monitor vendor performance against Service Level Agreements (SLAs) and Key Performance Indicators (KPIs); lead performance reviews and corrective action plans.
Identify and mitigate vendor‑related risks; manage scope changes and escalations with Clinical Operations, Science, Legal, and Finance.
Serve as the primary liaison between vendors and internal teams; provide regular status, financial, and risk updates to leadership.
Continuously improve vendor management processes and strengthen strategic vendor partnerships.
Clinical study management Manage key aspects of assigned clinical studies and related process improvement initiatives.
Develop and/or oversee essential study documentation, including protocols, case report forms,…