This position is open exclusively to current Northeastern University Co-Op students.
Work Period: January 2027 to June 2027. This is a full - time, 40 hours per week position with 5 days in office.
About Flagship Labs 111
Flagship Labs 111 Inc. (FL111) is a privately held, early-stage biotechnology company pioneering a novel platform harnessing innovations in chemistry, computation, and data science to create new therapeutic modalities beyond traditional small molecules. FL111 is backed by Flagship Pioneering, bringing the courage, vision, and resources to guide FL111 from platform validation to patient impact. We are seeking collaborative, creative and relentless problem solvers that share our passion for impact to join us!
About Flagship Pioneering
Flagship Labs 111 was founded by Flagship Pioneering's venture creation engine that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the company’s Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com .
Flagship Pioneering Co-Op Program
Welcome to Flagship Pioneering Co-Op Program for the cohort dreaming big and taking courageous leaps. You'll join fellow peers across our ecosystem of companies and learning firsthand how we build first-in-category companies. You’ll have access to enrichment sessions , a dedicated professional development track , and a mentor that help guide you toward your next step. By the end, you will carry on a meaningful project outcome , a genuine network , and a front-row view of how Flagship pioneer new ventures that change the world.
The Role
Design and execute cell-based experiments characterizing novel heterobifunctional molecules in cancer cell models.
Maintain, expand, and qualify a panel of cancer cell lines for ongoing studies.
Plan and run compound treatment experiments, including concentration-response, time-course, and combination studies.
Execute cell proliferation and viability assays to evaluate cellular response to treatment.
Perform Western blotting, qPCR, ELISA, and other cell-based PD assays to assess target engagement, pathway modulation, and downstream molecular effects.
Analyze data, generate figures and summaries, and interpret results against experimental hypotheses.
Review results with the team; help identify follow-up experiments, controls, and troubleshooting steps.
Develop, optimize, and document protocols to support reproducible execution across studies.
Maintain complete, accurate records in an electronic lab notebook ( ELN) — conditions, calculations, observations, deviations, raw data, and conclusions.
Present findings to scientists and project teams; collaborate with biology and chemistry colleagues on experimental planning and molecule characterization.
Key Responsibilities
By the end of the co-op, you will have contributed to a reproducible experimental workflow generating decision-quality data, evidenced by:
Cell lines consistently maintained and used with sound culture practice and documentation.
PD datasets with appropriate vehicle and positive/negative controls, documented replicates, and fit-for-purpose data-quality checks.
Clear analysis and interpretation of concentration-response…