Join Immatics and shape the future of cancer immunotherapy; one patient at a time!
Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME , a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.
Why Join Us?
Innovative Environment: Help to pioneer advancements in cancer immunotherapy.
Collaborative Culture: Be part of a diverse team dedicated to your professional growth.
Global Impact: Contribute to therapies that make a lasting impact on patients globally.
Role Overview:
We are seeking a Program Manager, CMC to lead and coordinate cross-functional Chemistry, Manufacturing, and Controls (CMC) activities within a cell therapy development and manufacturing environment. The Program Manager, CMC will drive planning, execution, and integration across manufacturing, analytical, quality, regulatory, and supply chain functions to support clinical development and commercialization goals. This role serves as a strategic partner across technical and operational teams, ensuring alignment, proactive risk management, and readiness for key milestones, including regulatory submissions and commercial manufacturing.
Reports to : Director, Program Management
Location : 13203 Murphy Road Suite 100 Stafford, TX 77477
Basic Qualifications:
Bachelor's degree in life sciences, medicine, immunology, oncology, pharmacy, health sciences, or a related field
5+ years of experience within biotechnology, pharmaceutical, or oncology-focused clinical development environments
Demonstrated experience in CMC programs and projects working cross-functionally within CMC activities, including manufacturing, quality, analytical, and regulatory operations
Academic or industry experience in cell and gene therapy, immunology/oncology, or bioprocessing/manufacturing sciences
Preferred Qualifications:
Advanced degree such as a Masters or PhD in life sciences, medicine, immunology, oncology, pharmacy, health sciences, or a related field
Experience supporting late-stage CMC programs in immunology, oncology, or cell and gene therapy
Proven experience managing programs and critical paths across multiple technical and operational functions
Proficiency with project management tools, dashboards, and reporting systems in regulated environments
Proven leadership, stakeholder management, and organizational skills with the ability to manage competing priorities in fast-paced environments
An ability to identify risks, drive decision-making, and implement process improvements across cross-functional teams
Experience coordinating external vendors, CMOs, CDMOs, or consulting partners
Strong communication and presentation skills with experience supporting senior leadership discussions and strategic planning
In this role you will:
Develop and maintain CMC program plans, timelines, risk registers, trackers, and reporting tools to support integrated program execution
Manage CMC deliverables, milestones, and critical paths while ensuring alignment with overarching development program timelines
Lead and facilitate cross-functional CMC meetings, including agenda development, documentation, action tracking, and follow-up activities
Drive collaboration across Manufacturing, Process Development, Analytical Development, Quality, Regulatory, Supply Chain, and Patient Operations teams
Coordinate and oversee activities with external vendors, contractors, CMOs, and CDMOs
Support strategic planning, governance, and decision-making activities with department leaders and senior management
Contribute to continuous improvement of CMC program management tools, processes, onboarding, and operational best practices
What do we offer?
At Immatics, we believe in investing in our team’s health, safety and well-being. Here’s what you can…