Job Description Summary
A laboratory in the Department of Neuroscience focused on understanding mechanisms associated with alcohol addiction is recruiting a technician to provide support in their ongoing studies. The job duties involve planning and carrying out routine experiments and techniques. This encompasses the organization and performance of behavioral studies in rats and mice, oversight of regulatory and compliance issues, and standard operating protocol implementation and development. Studies include behavioral research including voluntary alcohol drinking, as well as behavioral testing using models of stress, anxiety and aggression. In addition, the position will involve resource allocation (behavior room scheduling), rodent surgery, immunohistochemistry and microscopy for examination of rodent brain tissue, and viral vector injection into rodent brain and handling of BSL2 biohazards. The technician will also be required to handle rodents and maintaining animal colonies.
Entity
Medical University of South Carolina (MUSC - Univ)
Worker Type
Employee
Worker Sub-Type
Research Grant
Cost Center
CC000984 COM NEURO RES Operations CC
Pay Rate Type
Hourly
Pay Grade
University-GEN06
Pay Range
37,944.00 - 49,266.00 - 60,690.000
Scheduled Weekly Hours
40
Work Shift
Job Description
Job Purpose:
A laboratory in the Department of Neuroscience focused on understanding mechanisms associated with alcohol addiction is recruiting a technician to provide support in their ongoing studies. The job duties involve planning and carrying out routine experiments and techniques. This encompasses the organization and performance of behavioral studies in rats and mice, oversight of regulatory and compliance issues, and standard operating protocol implementation and development. Studies include behavioral research including voluntary alcohol drinking, as well as behavioral testing using models of stress, anxiety and aggression. In addition, the position will involve resource allocation (behavior room scheduling), rodent surgery, immunohistochemistry and microscopy for examination of rodent brain tissue, and viral vector injection into rodent brain and handling of BSL2 biohazards. The technician will also be required to handle rodents and maintaining animal colonies.
Additional Knowledge, skill, ability preferred:
Prior experience in preclinical rodent research is preferred, but not mandatory.
Guideline and Supervision:
The candidate will be directly supervised by the Principal Investigator and other senior lab personnel
Job Duties:
30% - Perform various experimental procedures including, but not limited to, executing behavioral protocols (testing mice on cognitive tasks) and alcohol self-administration studies, administering drugs by various routes of administration (injection, inhalation, infusion), preparing drugs and solutions, conducting stereotaxic surgery to implant chronic indwelling cannula in mice for long-term recordings or behavioral manipulations, facilitate data collection for fiber photometry and in vivo electrophysiology studies from mice during tasking measuring cognition, alcohol drinking, and anxiety-like behaviors.
20% - Perform various procedures for tissue and fluid specimen collection (e.g., brain slicing, brain extraction, blood collection), wet lab techniques including western immunoblotting, immunohistochemistry, RNA extraction and PCR, advanced microscopy techniques including confocal and light sheet microscopy in rodent brain tissue, and 3D image analysis using Imaris and other analytical software.
15% - Preparation and oversight of laboratory standard operating procedures (SOPs) and IACUC/IBC protocols, including writing and editing of laboratory procedures and submitting amendments to the IACUC/IBC protocols. Responsible for data management, including the collection, organization, and maintenance of behavioral and biological data sets within laboratory notebooks, servers and online document storage devices, as well…