Job Description
Our Research Scientists are our Inventors. We identify and target steps in disease mechanisms or pathways that could be inhibited or enhanced. Our goal is to use innovative thinking, state-of-the-art facilities, and robust scientific methodology, we collaborate to discover the next medical breakthrough.
As a Senior Scientist in the multiscale separations team within the Separations Sciences team of Analytical Enabling Capabilities, you will work within a highly collaborative team to enable the advancement of the development pipeline. You will be primarily responsible for chromatographic isolation of pharmaceutical API and impurities from analytical scale to semi-prep scale and prep scale, covering the space of small molecules, peptides, conjugate-based modalities as well as emerging modalities in our portfolio. To accelerate the development of new medicines and vaccines, you will partner with process chemists and analytical scientists to deploy efficient and fit-for-purpose chemical isolation methods, to establish innovative purification workflows, and to deliver high purity materials. As a member of our team, you will be joining a diverse group of scientific problem solvers, who are dedicated to creating the life-changing products of tomorrow.
Education Minimum Requirements:
Ph.D. in Synthetic Chemistry, Natural product chemistry, Analytical Chemistry or a related field.
M.S. with a minimum of 5 years of experience in the Biopharmaceutical industry.
Required Experience and Skills:
Experience in analytical, semi-prep/prep scale chromatography (RPLC, NPLC, SFC), technologies, instrumentation, and workflows, with demonstrated experience in its applications in chiral, achiral isolation of challenging pharmaceutical mixtures to support a variety of pharmaceutical modalities including small molecules, peptides, antibody-drug conjugates and vaccines adjuvants etc.
Experience in mass spectrometry and its application in MS-directed chromatographic purification.
Working knowledge of orthogonal detection technologies, including PDA, Multi-angle light scattering, charged aerosol detection etc.
Creative problem solving in scientific research and development, with proven track-record of translating R&D problem solving into impactful pipeline deliveries.
External scientific engagement that may include a combination of publications, industry white paper contributions, presentations at scientific meetings.
Excellent scientific writing and verbal communication skills.
Preferred Experience and Skills:
Experience working in the bio-pharmaceutical industry as Postdoc or intern is preferred.
EligibleforERP
Required Skills:
Analytical Chemistry, Analytical Method Development, Assay Development, Biopharmaceuticals, Chemical Synthesis, Chemistry, Chromatography, Mass Spectrometry (MS), Method Development, Purification Methods, Small Molecules, Synthetic Chemistry, Synthetic Organic Chemistry, Technical Writing, Ultra Performance Liquid Chromatography (UPLC)
Preferred Skills:
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