Job Description Summary
The laboratory of Dr. Federica del Monte at the Medical University of South Carolina (MUSC) is seeking a highly motivated individual to join an interdisciplinary research program focused on the heart-brain axis, protein misfolding, and proteotoxicity in neurodegenerative and cardiovascular diseases.
The successful candidate will have a degree in biomedical engineering and strong analytical background, experience with basic molecular biology for which to design and build devices for application in biomedical questions and specifically traumatic injuries. The candidate will have a genuine interest in protein homeostasis, cardiovascular and neurodegenerative disease mechanisms. The candidate will assist the Principal Investigator and the post-doctoral fellow. The candidate should be capable of conduct independent bioengineering and basic molecular biology experiments, managing a biological sample, and coordinating lab operations across interdisciplinary lines.
Entity
Medical University of South Carolina (MUSC - Univ)
Worker Type
Employee
Worker Sub-Type
Research Grant
Cost Center
CC000966 COM DOM CARD General CC
Pay Rate Type
Hourly
Pay Grade
University-GEN06
Pay Range
37,944.00 - 49,266.00 - 60,690.000
Scheduled Weekly Hours
40
Work Shift
Job Description
Job Duties:
35% – Develop devices to model traumatic injury and the effect of energy on protein folding. Examine samples after injury for structural and molecular changes.
35% – Assist laboratory staff with routine experimental procedures, including basic molecular and biochemical biology (e.g., Western blotting, polymerase chain reaction (PCR)/genotyping, qPCR), immunocytochemistry/immunohistochemistry (ICC/IHC), and high-resolution imaging of tissue structures and protein aggregates.
15% – Define and maintain accurate, up‑to‑date records of laboratory procedures, experimental protocols, equipment logs, and metadata in digital and/or hand‑written form. Track safety training and certification records for lab members, proactively contacting institutional safety offices as needed.
10% – Maintain, process, and characterize biological specimens (including human tissue samples, biobanked fluids, and murine tissues).
5% – Respond to occasional laboratory emergencies (e.g., -80°C freezer or liquid nitrogen malfunctions) in a timely manner, including during off‑hours when needed. Perform additional duties as requested by the PI to support ongoing general lab operations.
Preferred Requirements
A high school diploma and two years work experience in a clinical or research setting; a bachelor's degree in chemistry, biology, neuroscience, or other natural, life, or healthcare science may be substituted for the two years of required experience.
Additional Job Description
Minimum Requirements: A high school diploma and one year work experience in a clinical or research laboratory setting, in a health care setting or in a general maintenance or machine shop environment. A bachlor's degree in a related scientific discipline may be substituted for the required work experience.
Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all…