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Job Title:
Post Doctoral Scholar
Department:
EHE | Human Sciences Administration
Position Overview
The Health and Nutritional Metabolomics Laboratory at The Ohio State University is seeking a highly motivated Postdoctoral Scholar for an American Heart Association (AHA)-supported research program focused on developing and applying advanced metabolomics and lipidomics technologies to human clinical trial research.
The postdoctoral scholar will be jointly mentored by Dr. Chris Zhu and Dr. Colleen Spees , providing a unique opportunity to gain expertise in translational metabolomics, nutrition science, and clinical research. The successful candidate will work within a multidisciplinary team investigating the metabolic mechanisms underlying cardiometabolic diseases and other chronic health conditions through comprehensive analyses of samples collected from human intervention and clinical studies.
The Zhu Laboratory utilizes targeted and untargeted metabolomics, lipidomics, mass spectrometry, systems biology, and bioinformatics approaches to identify novel biomarkers and therapeutic targets. The Spees Laboratory has extensive expertise in clinical nutrition, dietary interventions, and patient-centered translational research.
Initial appointment: Two years (with an expected starting date of 4/1/2027 )
Renewal: Possible based on funding availability and satisfactory performance
Location: Columbus, Ohio
Additional Information:
Research Opportunities
The successful candidate will participate in cutting-edge research involving:
Targeted and untargeted metabolomics analyses of human clinical trial samples
Comprehensive lipidomics profiling for biomarker discovery
Integration of metabolomics and lipidomics data with clinical, dietary, and physiological outcomes
Identification of metabolic pathways associated with cardiovascular, metabolic, and chronic diseases
Development and application of advanced LC-MS-based analytical methods
Multi-omics data integration and systems biology approaches
Translation of omics discoveries into clinically relevant applications
Required Qualifications
Ph.D. in Analytical Chemistry, Chemistry, Biochemistry, Nutrition, Biomedical Sciences, Life Sciences, or a related discipline
Strong background in mass spectrometry-based metabolomics and/or lipidomics
Experience with LC-MS analyses and quantitative bioanalytical methods
Demonstrated publication record in peer-reviewed journals
Excellent analytical, problem-solving, and communication skills
Ability to work independently while contributing effectively within a collaborative team environment
Preferred Qualifications
Experience working with human clinical trial samples
Experience in targeted and untargeted metabolomics workflows
Experience in lipidomics analyses and interpretation
Knowledge of bioinformatics and statistical tools, including R, MetaboAnalyst, Python, Cytoscape, or related software
Experience integrating omics data with clinical or dietary outcomes
Research experience in cardiovascular disease,…