- Pay
- $59–77k
- Where
- Smilow Center for Translational
- Level
- Mid
University Overview
The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning. As an employer Penn has been ranked nationally on many occasions with the most recent award from Forbes who named Penn one of America’s Best Large Employers in 2023.
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The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.
Posted Job Title
Research Specialist C/D
Job Profile Title
Research Specialist C
Job Description Summary
The Penn-CHOP Lung Biology Institute in the Department of Medicine at the University of Pennsylvania is seeking to hire a highly skilled histopathologist as a Research Specialist C to join a dynamic and cutting-edge research team exploring regenerative lung biology. The Research Specialist C position will be responsible for working independently to perform precision tissue processing via cryostat, vibratome and microtome to produce extremely thin and uniform histological slices, perform complex histological techniques including hematoxylin and eosin staining, novel antibody staining/quality control testing, antigen retrieval processes, in situ hybridization, RNAScope, 3D spatial techniques such as 10XVisium and other emerging imaging techniques. The candidate will also be expected to train and supervise laboratory stuff on histopathology protocols and maintain large histology databases for the institute. They will also be expected to interact daily with senior researchers to jointly produce publication quality staining and images, contribute to the development of new techniques, generate data for top tier research publications and grant applications, assist with general laboratory maintenance duties and be given the opportunity to accomplish independent research projects and advance their own education.
Job Description
This position is contingent upon favorable funding.
Research Specialist C
Job Responsibilities
Perform tissue paraffin and agarose embedding and perform various sectioning techniques such as Microtome, Cryostat and Vibratome and Compresstome tissue sectioning (microns thick) of human and mouse samples and perform immunohistochemistry, immunofluorescence and affinity based chemical reactions on these slides for downstream antigen analyses.
Perform highly sensitive methodologies to quantitate RNA transcript levels (RNAScope), optimizing RNA probes across multiple transcripts and combine with traditional immunohistochemistry techniques.
Perform 3D spatial transcriptomics and other 3D histology next generation sequencing platforms.
Collaborate with senior lab members to discuss projects and results, develop independent long term project goals, assist with the generation and preparation of data for the submission of manuscripts and grants.
Ensure that paraffin embedded sections are carefully organized and catalogued for human and mouse biorepository and databases for antibodies and all experimental conditions and results are recorded and…