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Posted Job Title
Research Specialist D
Job Profile Title
Research Specialist D
Job Description Summary
The Breast Cancer Translational Research Group seeks a Research Specialist D to lead our translational research program involving bench to bedside investigations. This scientist will serve as the Laboratory Manager and Quantitative Imaging Lead. They will independently design experiments, analyze and interpret data, and write scientific manuscripts while overseeing daily laboratory operations and mentoring all laboratory personnel.
A major component of this position is hands-on quantitative analysis of small-animal imaging studies evaluating novel radiotracers, including image processing, kinetic modeling, and longitudinal assessment of treatment response. The individual will manage large research datasets, perform statistical analyses, and develop reproducible computational workflows. They must be able to interact with the EHR. Working directly with the principal investigator, this person will coordinate research activities across the laboratory and meet weekly with each laboratory member to review raw data, assess progress, troubleshoot problems, and establish next steps.
Job Description
Job Responsibilities
Independent Experimental Design and Scientific Writing Independently develop experimental designs and detailed study protocols, including hypotheses, appropriate controls, quantitative endpoints, and analysis plans for animal imaging, radiotracer characterization, and translational breast cancer studies.
Independently analyze and interpret experimental findings, select and validate analytical methods, evaluate statistical and biological significance, and design follow-up experiments.
Independently prepare complete scientific manuscript drafts, including methods, results, discussion, figures, and tables; coordinate coauthor input and prepare revisions and responses to peer reviewers.
Prepare abstracts, presentations, and research summaries, and contribute scientific content and preliminary data to grant applications and progress reports.
Animal Image Analysis, Radiotracer Kinetics, and Computational Modeling Lead quantitative analysis of static and dynamic small-animal PET and PET/CT studies evaluating novel radiotracers in breast cancer models, including patient-derived xenografts and other mouse tumor models.
Perform three-dimensional image registration, tumor and organ segmentation, longitudinal volume-of-interest tracking, and extraction of tissue and blood-pool time–activity curves.
Quantify tumor uptake, normal-organ distribution, tracer…