Job Description
General Summary
The Associate Director, Global Pain Forecasting & Analytics will join the Global Forecasting & Analytics team within the Commercial organization to lead forecasting and analytics for Vertex’s global Pain portfolio, spanning current programs and future pipeline assets. This role will serve as a key partner to the Global Pain Marketing Lead and Global Commercial Strategy, leading the development and evolution of forecast models that support long-range planning, near-term operations, commercialization decisions, and cross-functional alignment across Pain disease areas.
The Associate Director will build, maintain, and continuously evolve Vertex’s global Pain forecasting capabilities. This includes developing a deep understanding of the evolving Pain landscape and integrating clinical data, competitive intelligence, analog performance, key market drivers, and broader market dynamics into robust forecasting models. This individual will synthesize complex quantitative and qualitative inputs into actionable recommendations for senior leadership and support key decision-making across R&D, Marketing, Global Commercial Strategy, Finance, and other cross-functional partners.
As a core member of the Global Commercial Brand Teams for Pain, this leader will maintain a pulse on critical business questions and help shape the analytical approach needed to support them. A strong preference will be given to candidates with prior in-line forecasting experience, ideally supporting marketed products, who can bring practical commercial perspective and operational discipline to the Global Forecasting team.
Key Duties and Responsibilities
Lead the design, development, refinement, and ongoing evolution of global Pain forecast models across current and future assets.
Support long-range planning and ongoing scenario planning through robust and adaptable forecasting approaches.
Develop and maintain operational forecasting models that incorporate new data, market signals, inventory trends, emerging insights, and evolving assumptions.
Own and enhance forecast frameworks, model logic, analog selections, data sources, and research-informed assumptions.
Deliver high-quality forecast outputs with clear articulation of assumptions, sensitivities, risks, and uncertainties.
Serve as the primary forecasting partner to the Global Pain Marketing Lead and Global Commercial Strategy, providing objective perspective, commercial insight, and forecasting rigor.
Synthesize complex data sets into clear, actionable recommendations for senior leadership.
Incorporate epidemiology, claims analysis, analogs, qualitative insights, competitive intelligence, access dynamics, and broader market developments into forecast assumptions.
Maintain a strong understanding of the evolving Pain market, including treatment dynamics, competitive shifts, and the broader market context in which Vertex’s assets will compete.
Support analyses that help characterize demand, treatment flow, and potential movement of patients across existing therapies and future treatment options.
Ensure key performance indicators can be clearly derived from forecast models and used to track and explain forecasted performance.
Build forecast structures that enable transparent performance drivers, clear output interpretation, and effective scenario evaluation.
Apply familiarity with relevant internal and external data sources to ensure forecasting assumptions are well supported and connected to the broader Pain data strategy.
Partner cross-functionally with Global Marketing, Global Commercial Strategy, Global Pricing & Market Access, Finance, HEOR, Medical Affairs, Clinical Development, Commercial Strategy, and regional partners.
Coordinate analytics alignment across functions to ensure consistency in forecasting assumptions and key drivers.
Maintain strong communication with regional commercial partners to integrate market-specific insights into global forecasts.
Partner with internal…