Job Description
General Summary:
The Formulation Senior Research Associate will perform an array of activities working with other scientists to advance drug candidates from exploratory development through commercial line extension in a Quality by Design (QbD) environment using lab based and computational tools.
Key Duties and Responsibilities:
Contribute to the development of solid dosage forms for clinical and commercial use, generate data for project progression and regulatory filings, conduct a range of activities for optimization and scale up studies
Help execute, and interpret laboratory experiments, with minimal supervision, to meet established project timelines
Maintain accurate and complete laboratory notebook capturing protocols, results and observations
Interpret data to form sound conclusions
Timely document integrated experimental outcomes in presentations and research reports
Perform basic statistical analysis of experimental data
Assist in technical transfer to CMO partners for clinical trial manufacture
Initiate experimental troubleshooting on routine problems, with minimal supervision
Contribute to drafting regulatory filing documentation
Comply with all relevant Safety and GMP procedures
Knowledge and Skills:
Sound technical knowledge of pharmaceutical and engineering principles in the solid dosage form development for both clinical and commercial scales
Hands on experience with formulation techniques, processing equipment, and unit operations at both the laboratory and clinical manufacturing scales
Strong math skills particularly as applied to material/energy balances, and intermediate applied statistical analysis
Strong technical writing skills
Strong verbal and written communication skills
Successful and efficient multitasking and ability to work on a few projects concurrently
Detail-oriented
Direct experience working with CMOs is a plus
Understanding of QbD and experience with Regulatory filings is a plus
Strong background in oral solid form development and good understanding of material properties
Education and Experience:
Bachelor’s degree in pharmaceutical, material science or chemical engineering field
Master's Degree in pharmaceutical sciences, chemistry, chemical engineering, materials sciences or related field and 0-2 years experience in life sciences, engineering or academia, or
Bachelor's Degree in pharmaceutical sciences, chemistry, chemical engineering, materials sciences or related field and 4 years experience in life sciences, engineering or academia
At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Pay Range:
$74,000 - $111,000
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex…