Zura is a clinical‑stage biotechnology company advancing clinical development of novel therapeutic candidates for autoimmune and inflammatory diseases with significant unmet medical need. Our work is focused on understanding immune‑mediated disease and translating that science into carefully designed clinical programs, with patients and their challenges guiding our approach.
Zura is building and advancing a growing portfolio of clinical programs informed by strong scientific expertise and disciplined execution. Across the organization, teams work closely together to progress development thoughtfully, with a shared emphasis on data quality, rigor, and integrity.
At Zura, we operate as One Zura. This means collaborating across functions, valuing diverse perspectives, and taking shared ownership of our work—from problem‑solving to execution. Joining Zura means contributing to patient‑focused clinical development in a hands‑on environment where individual effort matters, collaboration is expected, and people are encouraged to grow while working toward a common goal.
What You’ll Do:
The Director, Clinical Operations is a senior leader accountable for the operational delivery of Zura Bio’s global clinical development programs, including Phase 3 studies supporting BLA/NDA submissions. This role serves as the key point of accountability for clinical trial delivery, ensuring studies are executed to the highest standards of quality, speed, and regulatory compliance to support successful registrations and future commercialization.
The Director, Clinical Operations provides functional leadership in a fast-paced biotech environment, helping shape the Clinical Operations operating model and working closely with internal cross functional teams and external partners (CROs, vendors, investigative sites). Director, clin ops combine strong oversight of an outsourced trial model with inspection readiness, disciplined budget and financial management, and a commitment to continuous improvement through analytics, risk-based approaches, and emerging technologies, including AI-enabled tools. The role requires strong judgment, operational rigor, and the ability to balance strategy with execution in a resource-conscious organization.
Responsibilities:
Clinical Operations Strategy & Leadership
Define and implement the clinical operations strategy in alignment with Zura Bio’s corporate and development objectives.
Contribute to Clinical Development Plans and translate clinical strategy into integrated operational plans, timelines, and roadmaps aligned with key development milestones.
Work cross-functionally to ensure alignment of activities across functions and clarify interdependencies.
Serve as the senior Clinical Operations representative on cross functional workstreams and in senior leadership forums.
Ensure operational considerations are embedded early in clinical development plans and protocols.
Partner with senior clinical, regulatory, and functional leadership to support portfolio prioritization, investment trade-off decisions, and execution strategy.
Where appropriate, recruit, hire, and line manage Clinical Operations professionals to ensure effective execution of clinical project plans and corporate objectives.
As the company grows, contribute to the development of a best-in-class Clinical Operations function, including selection and implementation of optimized systems and processes.
Evaluate and, where appropriate, pilot AI-enabled and automation tools (e.g., for feasibility, site selection, enrollment forecasting, and document drafting) to improve speed, quality, and efficiency, with appropriate governance and validation.
Trial Execution & Delivery
Provide leadership and oversight for the planning, start-up, conduct, and closeout of global clinical trials.
Ensure robust, integrated study plans, timelines, and budgets are in place to support high-quality execution and portfolio transparency.
Review and approve feasibility assessments and…